产品货号：
Z18317
中文名称：
IL31抗体
英文名称：
Anti-IL31 Antibody
产品规格：
0.1mg
发货周期：
1～3天
产品价格：
询价
| 抗体名称 | Anti-IL31 Antibody |
| 指标别名 | IL 31;IL31;IL-31;interleukin 31 |
| 克隆性 | Polyclonal |
| 检验物种 | mouse |
| 应用范围 | ELISA,WB,IHC |
| 基因名称 | IL31 |
| 抗体来源 | Rabbit |
| 抗体类型 | IgG |
| 免疫原 | IL-31 antibody was raised against a 16 amino acid synthetic peptide from near the amino terminus of mouse IL-31.The immunogen is located within amino acids 30 - 80 of IL-31. |
| 计算分子量 | 18kDa |
| 成分 | IL-31 Antibody is supplied in PBS containing 0.02% sodium azide. |
| 纯化方式 | IL-31 Antibody is affinity chromatography purified via peptide column. |
| 浓度 | 1mg/mL |
| 产品形态 | 溶液 |
| 保存条件 | 4℃可保存3个月，-20℃可保存1年。 |
| 背景资料 | Interleukin-31 (IL-31) is a recently discovered T-cell cytokine closely related to IL-6 type cytokines and is preferentially produced by T helper type 2 cells.IL-31 activity is mediated through the ligand-induced oligomerization of a dimeric receptor complex containing IL-31 receptor A and oncostatin M receptor.In response to IL-31 binding,these proteins activate the JAK/STAT and the AKT signaling pathways.RNA levels of IL-31 receptor A and oncostatin M receptor are induced in activated monocytes but are expressed constitutively in epithelial cells.IL-31,when overexpressed in transgenic mice,results in the development of pruritis,alopecia,and skin lesions and in humans may result in atopic dermatitis,suggesting that IL-31 may represent a novel target for antipruritic drug development. |
| Uniprot ID | Q6EAL8 |
| 基因名全称 | Interleukin 31 |
| 蛋白名全称 | Interleukin 31 |
| 推荐稀释比 | IL-31 antibody can be used for the detection of IL-31 by Western blot at 2.5 ～ 10μg/mL.Antibody can also be used for immunohistochemistry starting at 10μg/mL.Antibody validated:Western Blot in mouse samples and Immunohistochemistry in rat samples.All other applications and species not yet tested. |
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